Article
Genetic contributions to lupus nephritis in a multi-ethnic cohort of systemic lupus erythematous patients.
PloS one - 1 Jan 2018
Lanata Cristina M, Nititham Joanne, Taylor Kimberly E, Chung Sharon A, Torgerson Dara G, Seldin Michael F, Pons-Estel Bernardo A, Tusié-Luna Teresa, Tsao Betty P, Morand Eric F, Alarcón-Riquelme Marta E, Criswell Lindsey A
Abstract excerpt
OBJECTIVE: African Americans, East Asians, and Hispanics with systemic lupus erythematous (SLE) are more likely to develop lupus nephritis (LN) than are SLE patients of European descent. The etiology of this difference is not clear, and this study was undertaken to investigate how genetic variants might explain this effect. METHODS: In this cross-sectional study, 1244 SLE patients from multiethnic case...
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