Article
Impact of genetic ancestry and sociodemographic status on the clinical expression of systemic lupus erythematosus in American Indian-European populations.
Arthritis and rheumatism - 1 Nov 2012
Sánchez Elena, Rasmussen Astrid, Riba Laura, Acevedo-Vasquez Eduardo, Kelly Jennifer A, Langefeld Carl D, Williams Adrianne H, Ziegler Julie T, Comeau Mary E, Marion Miranda C, García-De La Torre Ignacio, Maradiaga-Ceceña Marco A, Cardiel Mario H, Esquivel-Valerio Jorge A, Rodriguez-Amado Jacqueline, Moctezuma José Francisco, Miranda Pedro, Perandones Carlos E, Castel Cecilia, Laborde Hugo A, Alba Paula, Musuruana Jorge L, Goecke I Annelise, Anaya Juan-Manuel, Kaufman Kenneth M, Adler Adam, Glenn Stuart B, Brown Elizabeth E, Alarcón Graciela S, Kimberly Robert P, Edberg Jeffrey C, Vilá Luis M, Criswell Lindsey A, Gilkeson Gary S, Niewold Timothy B, Martín Javier, Vyse Timothy J, Boackle Susan A, Ramsey-Goldman Rosalind, Scofield R Hal, Petri Michelle, Merrill Joan T, Reveille John D, Tsao Betty P, Orozco Lorena, Baca Vicente, Moser Kathy L, Gaffney Patrick M, James Judith A, Harley John B, Tusié-Luna Teresa, Pons-Estel Bernardo A, Jacob Chaim O, Alarcón-Riquelme Marta E
Abstract excerpt
OBJECTIVE: American Indian-Europeans, Asians, and African Americans have an excess morbidity from systemic lupus erythematosus (SLE) and a higher prevalence of lupus nephritis than do Caucasians. The aim of this study was to analyze the relationship between genetic ancestry and sociodemographic characteristics and clinical features in a large cohort of American Indian-European SLE patients. METHODS: A total of...
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