Article
Genetic polymorphism of PRKCDBP is associated with an increased risk of endometrial cancer.
Cancer investigation - 1 Nov 2012
Tong Seo-Yun, Lee Jong-Min, Ki Kyung-Do, Seol Hyun-Joo, Choi Young-Joon, Lee Seon-Kyung
Abstract excerpt
PRKCDBP is a putative tumor suppressor located at 11p15.4, where frequent genomic loss has been observed in human cancers. We explored the possible association between an intra-exonic single nucleotide polymorphism (SNP), rs1051992, that results in a Leu to Pro substitution, and risk for endometrial carcinogenesis. We assessed the genotype of rs1051992 in endometrial cancer tissues from 147 patients and normal...
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