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Article

Association of a single nucleotide polymorphism at 6q25.1,rs2046210, with endometrial cancer risk among Chinese women.

Chinese journal of cancer - 1 Feb 2011

Li Guoliang, Xiang Yong-Bing, Courtney Regina, Cheng Jia-Rong, Huang Bo, Long Ji-Rong, Cai Hui, Zheng Wei, Shu Xiao-Ou, Cai Qiuyin

Abstract excerpt

A recent genome-wide association study identified a new susceptibility locus for breast cancer, rs2046210, which is a single nucleotide polymorphism (SNP) located upstream of the estrogen receptor α(ESR1) gene on chromosome 6q25.1. Given that endometrial cancer shares many risk factors with breast cancer and both are related to estrogen exposure and that rs2046210 is in close proximity to the ESR1 gene, we...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21272446
DOI: 10.5732/cjc.010.10516
PMCID: PMC3842219

Genes

ESR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Association of a single nucleotide polymorphism at 6q25.1,rs2046210, with endometrial cancer risk among Chinese women.PMID 21272446Read ↗

Association between a novel polymorphism (rs2046210) of the 6q25.1 locus and breast cancer risk.Semantic proximity Read ↗

Eight functional polymorphisms in the estrogen receptor 1 gene and endometrial cancer risk: a meta-analysis.Semantic proximity Read ↗

A common polymorphism near the ESR1 gene is associated with risk of breast cancer: evidence from a case-control study and a meta-analysis.Semantic proximity Read ↗

Relationships of physical and breast cancer phenotypes with three single-nucleotide polymorphisms (rs2046210, rs3757318, and rs3803662) associated with breast cancer risk in Japanese women.Semantic proximity Read ↗

Genome-wide association study identifies a common variant associated with risk of endometrial cancer.Semantic proximity Read ↗

Impact of ESR1 Polymorphisms on Risk of Breast Cancer in the Chinese Han Population.Semantic proximity Read ↗

Genome-wide association study identifies a new breast cancer susceptibility locus at 6q25.1.Semantic proximity Read ↗

Meta-Analysis of 49 SNPs Covering 25,446 Cases and 41,106 Controls Identifies Polymorphisms in Hormone Regulation and DNA Repair Genes Associated with Increased Endometrial Cancer Risk.Semantic proximity Read ↗

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