Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

APOBEC3A/B deletion polymorphism and endometrial cancer risk.

Cancer medicine - 1 Mar 2023

Sofiyeva Nigar, Krakstad Camilla, Halle Mari K, O'Mara Tracy A, Romundstad Pål, Hveem Kristian, Vatten Lars, Lønning Per E, Gansmo Liv B, Knappskog Stian

Abstract excerpt

BACKGROUND: A common 30 kb deletion affecting the APOBEC3A and APOBEC3B genes has been linked to increased APOBEC activity and APOBEC-related mutational signatures in human cancers. The role of this deletion as a cancer risk factor remains controversial. MATERIALS AND METHODS: We genotyped the APOBEC3A/B deletion in a sample of 1,470 Norwegian endometrial cancer cases and compared to 1,918 healthy controls. For...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Cytidine Deaminase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endometrial Neoplasms

Share to Minor Histocompatibility Antigens

Share to Polymorphism, Single Nucleotide

Share to Proteins

Share to Risk Factors

Share to Sequence Deletion

Source

Open in PubMed Open full text

Identifiers

PMID: 36394079
DOI: 10.1002/cam4.5448
PMCID: PMC10067079

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

APOBEC3A/B deletion polymorphism and endometrial cancer risk.PMID 36394079Read ↗

Impact of the APOBEC3A/B deletion polymorphism on risk of ovarian cancer.Semantic proximity Read ↗

APOBEC3A/B deletion polymorphism and cancer risk.Semantic proximity Read ↗

APOBEC3 deletion polymorphism is associated with epithelial ovarian cancer risk among Chinese women.Semantic proximity Read ↗

APOBEC3 deletion polymorphism is associated with breast cancer risk among women of European ancestry.Semantic proximity Read ↗

APOBEC3 deletion increases the risk of breast cancer: a meta-analysis.Semantic proximity Read ↗

Impact of functional germline variants and a deletion polymorphism in APOBEC3A and APOBEC3B on breast cancer risk and survival in a Swedish study population.Semantic proximity Read ↗

Germline copy number variants and endometrial cancer risk.Semantic proximity Read ↗

The 30 kb deletion in the APOBEC3 cluster decreases APOBEC3A and APOBEC3B expression and creates a transcriptionally active hybrid gene but does not associate with breast cancer in the European populationSemantic proximity Read ↗

Population stratification of a common APOBEC gene deletion polymorphism.Semantic proximity Read ↗

Endometrial Cancer, BRCA1, and BRCA2 in the UK Biobank Cohort.Semantic proximity Read ↗

APOBEC3A is an oral cancer prognostic biomarker in Taiwanese carriers of an APOBEC deletion polymorphismSemantic proximity Read ↗

The influence of the Cyclin D1 870 G>A polymorphism as an endometrial cancer risk factor.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.