Article
Topoisomerase IIβ binding protein 1 c.*229C>T (rs115160714) gene polymorphism and endometrial cancer risk.
Pathology oncology research : POR - 1 Jul 2014
Forma Ewa, Wójcik-Krowiranda Katarzyna, Jóźwiak Paweł, Szymczyk Agnieszka, Bieńkiewicz Andrzej, Bryś Magdalena, Krześlak Anna
Abstract excerpt
TopBP1 (topoisomerase IIβ binding protein 1) protein is involved in DNA replication, DNA damage checkpoint response and transcriptional regulation. In this study we investigated whether alterations in the TopBP1 gene can influence the risk of endometrial cancer. We examined the association between five single nucleotide polymorphisms (rs185903567, rs116645643, rs115160714, rs116195487, and rs112843513) located in...
