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Article

Nonrandom X chromosome inactivation is influenced by multiple regions on the murine X chromosome.

Genetics - 1 Nov 2012

Thorvaldsen Joanne L, Krapp Christopher, Willard Huntington F, Bartolomei Marisa S

Abstract excerpt

During the development of female mammals, one of the two X chromosomes is inactivated, serving as a dosage-compensation mechanism to equalize the expression of X-linked genes in females and males. While the choice of which X chromosome to inactivate is normally random, X chromosome inactivation can be skewed in F1 hybrid mice, as determined by alleles at the X chromosome controlling element (Xce), a locus defined...

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Identifiers

PMID: 22887817
DOI: 10.1534/genetics.112.144477
PMCID: PMC3522153

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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