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Article

Genetic control of X chromosome inactivation in mice: definition of the Xce candidate interval.

Genetics - 1 Aug 2006

Chadwick Lisa Helbling, Pertz Lisa M, Broman Karl W, Bartolomei Marisa S, Willard Huntington F

Abstract excerpt

In early mammalian development, one of the two X chromosomes is silenced in each female cell as a result of X chromosome inactivation, the mammalian dosage compensation mechanism. In the mouse epiblast, the choice of which chromosome is inactivated is essentially random, but can be biased by alleles at the X-linked X controlling element (Xce). Although this locus was first described nearly four decades ago, the...

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Identifiers

PMID: 16582439
DOI: 10.1534/genetics.105.054882
PMCID: PMC1569705

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Genetic control of X chromosome inactivation in mice: definition of the Xce candidate interval.PMID 16582439Read ↗

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Genetic and parent-of-origin influences on X chromosome choice in Xce heterozygous mice.Semantic proximity Read ↗

Xce haplotypes show modified methylation in a region of the active X chromosome lying 3' to Xist.Semantic proximity Read ↗

Xite, X-inactivation intergenic transcription elements that regulate the probability of choice.Semantic proximity Read ↗

Structural organization of the inactive X chromosome in the mouse.Semantic proximity Read ↗

Non-random X chromosome inactivation in mammalian cells.Semantic proximity Read ↗

Regulation of X-chromosome inactivation by the X-inactivation centre.Semantic proximity Read ↗

A long noncoding RNA influences the choice of the X chromosome to be inactivated.Semantic proximity Read ↗

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