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Article

Regulation of X-chromosome inactivation by the X-inactivation centre.

Nature reviews. Genetics - 1 Jun 2011

Augui Sandrine, Nora Elphège P, Heard Edith

Abstract excerpt

X-chromosome inactivation (XCI) ensures dosage compensation in mammals and is a paradigm for allele-specific gene expression on a chromosome-wide scale. Important insights have been made into the developmental dynamics of this process. Recent studies have identified several cis- and trans-acting factors that regulate the initiation of XCI via the X-inactivation centre. Such studies have shed light on the...

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Identifiers

PMID: 21587299
DOI: 10.1038/nrg2987

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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