Article
Xce haplotypes show modified methylation in a region of the active X chromosome lying 3' to Xist.
Proceedings of the National Academy of Sciences of the United States of America - 11 Apr 1995
Courtier B, Heard E, Avner P
Abstract excerpt
During early mammalian embryogenesis, one of the two X chromosomes in somatic cells of the female becomes inactivated through a process that is thought to depend on a unique initiator region, the X-chromosome inactivation center (Xic). The recently characterized Xist sequence (X-inactive-specific transcript) is thought to be a possible candidate for Xic. In mice a further genetic element, the X...
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