Article
Xce haplotypes show modified methylation in a region of the active X chromosome lying 3' to Xist.
Proceedings of the National Academy of Sciences of the United States of America - 11 Apr 1995
Courtier B, Heard E, Avner P
Abstract excerpt
During early mammalian embryogenesis, one of the two X chromosomes in somatic cells of the female becomes inactivated through a process that is thought to depend on a unique initiator region, the X-chromosome inactivation center (Xic). The recently characterized Xist sequence (X-inactive-specific...
Topics
- Animals
- DNA
- DNA Restriction-Modification Enzymes
- Deoxyribonuclease HpaII
- Deoxyribonucleases, Type II Site-Specific
- Dosage Compensation, Genetic
- Female
- Genetic Variation
- Haplotypes
- Male
- Methylation
- Mice
