Article
Alzheimer's disease risk gene, GAB2, is associated with regional brain volume differences in 755 young healthy twins.
Twin research and human genetics : the official journal of the International Society for Twin Studies - 1 Jun 2012
Hibar Derrek P, Jahanshad Neda, Stein Jason L, Kohannim Omid, Toga Arthur W, Medland Sarah E, Hansell Narelle K, McMahon Katie L, de Zubicaray Greig I, Montgomery Grant W, Martin Nicholas G, Wright Margaret J, Thompson Paul M
Abstract excerpt
The development of late-onset Alzheimer's disease (LOAD) is under strong genetic control and there is great interest in the genetic variants that confer increased risk. The Alzheimer's disease risk gene, growth factor receptor bound protein 2-associated protein (GAB2), has been shown to provide a 1.27-1.51 increased odds of developing LOAD for rs7101429 major allele carriers, in case-control analysis. GAB2 is...
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