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Article

General dimensions of human brain morphometry inferred from genome-wide association data.

Human brain mapping - 1 Jun 2023

Fürtjes Anna E, Arathimos Ryan, Coleman Jonathan R I, Cole James H, Cox Simon R, Deary Ian J, de la Fuente Javier, Madole James W, Tucker-Drob Elliot M, Ritchie Stuart J

Abstract excerpt

Understanding the neurodegenerative mechanisms underlying cognitive decline in the general population may facilitate early detection of adverse health outcomes in late life. This study investigates genetic links between brain morphometry, ageing and cognitive ability. We develop Genomic Principal Components Analysis (Genomic PCA) to model general dimensions of brain-wide morphometry at the level of their...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 36987996
DOI: 10.1002/hbm.26283
PMCID: PMC10171533

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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