Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Common variant in GAB2 is associated with late-onset Alzheimer's disease in Han Chinese.

Clinica chimica acta; international journal of clinical chemistry - 20 Feb 2011

Zhong Xiao-Ling, Yu Jin-Tai, Hou Gui-Ying, Xing Yao-Yao, Jiang Hong, Li Yang, Tan Lan

Abstract excerpt

BACKGROUND: GRB-associated binding protein 2 (GAB2) may function as a risk factor in the pathogenesis of Alzheimer disease (AD). A recent large genome-wide association study (GWAS) has identified a significant association of rs10793294 polymorphism within the GAB2 gene with AD in Caucasians. While there are no studies on the association of rs10793294 polymorphism with AD risk in the Chinese population. METHODS:...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Adaptor Proteins, Signal Transducing
Share to Age of Onset
Share to Alzheimer Disease
Share to Asian People
Share to China
Share to Ethnicity
Share to Polymorphism, Genetic
Share to Regression Analysis

Source

Identifiers

PMID: 21108942
DOI: 10.1016/j.cca.2010.11.022

Genes

GAB2
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Common variant in GAB2 is associated with late-onset Alzheimer's disease in Han Chinese.PMID 21108942Read ↗

Associations of rs3740677 within GAB2 Gene with LOAD in Chinese Han Population.Semantic proximity Read ↗

Association study of the GAB2 gene with the risk of Alzheimer disease in the chinese population.Semantic proximity Read ↗

GAB2 is not associated with late-onset Alzheimer's disease in Chinese Han.Semantic proximity Read ↗

Linking protective GAB2 variants, increased cortical GAB2 expression and decreased Alzheimer's disease pathology.Semantic proximity Read ↗

GAB2 alleles modify Alzheimer's risk in APOE epsilon4 carriers.Semantic proximity Read ↗

Common variation in GRB-associated Binding Protein 2 (GAB2) and increased risk for Alzheimer dementia.Semantic proximity Read ↗

GAB2 is not associated with late-onset Alzheimer's disease in Japanese.Semantic proximity Read ↗

GAB2 polymorphism rs2373115 confers susceptibility to sporadic Alzheimer's disease.Semantic proximity Read ↗

GAB2 as an Alzheimer disease susceptibility gene: follow-up of genomewide association results.Semantic proximity Read ↗

The GAB2 gene and the risk of Alzheimer's disease: replication and meta-analysis.Semantic proximity Read ↗

The genetic variation of ARRB2 is associated with late-onset Alzheimer's disease in Han Chinese.Semantic proximity Read ↗

Genetic association of BIN1 and GAB2 in Alzheimer's disease: A meta-analysis and systematic review.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.