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Article

Influenza virus resistance to human neutralizing antibodies.

mBio - 1 Jan 2012

Crowe James E

Abstract excerpt

The human antibody repertoire has an exceptionally large capacity to recognize new or changing antigens through combinatorial and junctional diversity established at the time of V(D)J recombination and through somatic hypermutation. Influenza viruses exhibit a relentless capacity to escape the human antibody response by altering the amino acids of their surface proteins in hypervariable domains that exhibit a...

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Share to Antibodies, Neutralizing
Share to Antibodies, Viral
Share to Hemagglutinin Glycoproteins, Influenza Virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Influenza, Human

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Share to Orthomyxoviridae

Source

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Identifiers

PMID: 22851660
DOI: 10.1128/mBio.00213-12
PMCID: PMC3419524

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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