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Article

Methylene blue protects against TDP-43 and FUS neuronal toxicity in C. elegans and D. rerio.

PloS one - 1 Jan 2012

Vaccaro Alexandra, Patten Shunmoogum A, Ciura Sorana, Maios Claudia, Therrien Martine, Drapeau Pierre, Kabashi Edor, Parker J Alex

Abstract excerpt

The DNA/RNA-binding proteins TDP-43 and FUS are found in protein aggregates in a growing number of neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS) and related dementia, but little is known about the neurotoxic mechanisms. We have generated Caenorhabditis elegans and zebr...

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Source

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Identifiers

PMID: 22848727
DOI: 10.1371/journal.pone.0042117
PMCID: PMC3407135

Genes

FUS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-22848727-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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