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Article

Rescue of ATXN3 neuronal toxicity in Caenorhabditiselegans by chemical modification of endoplasmic reticulum stress.

Disease models & mechanisms - 19 Dec 2017

Fardghassemi Yasmin, Tauffenberger Arnaud, Gosselin Sarah, Parker J Alex

Abstract excerpt

Polyglutamine expansion diseases are a group of hereditary neurodegenerative disorders that develop when a CAG repeat in the causative genes is unstably expanded above a certain threshold. The expansion of trinucleotide CAG repeats causes hereditary adult-onset neurodegenerative disorders, such as Huntington's disease, dentatorubral-pallidoluysian atrophy, spinobulbar muscular atrophy and multiple forms of...

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Identifiers

PMID: 29061563
DOI: 10.1242/dmm.029736
PMCID: PMC5769603

Genes

ATXN3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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