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Article

Genetic markers enhance coronary risk prediction in men: the MORGAM prospective cohorts.

PloS one - 1 Jan 2012

Hughes Maria F, Saarela Olli, Stritzke Jan, Kee Frank, Silander Kaisa, Klopp Norman, Kontto Jukka, Karvanen Juha, Willenborg Christina, Salomaa Veikko, Virtamo Jarmo, Amouyel Phillippe, Arveiler Dominique, Ferrières Jean, Wiklund Per-Gunner, Baumert Jens, Thorand Barbara, Diemert Patrick, Trégouët David-Alexandre, Hengstenberg Christian, Peters Annette, Evans Alun, Koenig Wolfgang, Erdmann Jeanette, Samani Nilesh J, Kuulasmaa Kari, Schunkert Heribert

Abstract excerpt

BACKGROUND: More accurate coronary heart disease (CHD) prediction, specifically in middle-aged men, is needed to reduce the burden of disease more effectively. We hypothesised that a multilocus genetic risk score could refine CHD prediction beyond classic risk scores and obtain more precise risk...

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Identifiers

PMID: 22848412
DOI: 10.1371/journal.pone.0040922
PMCID: PMC3405046

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22848412-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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