Article
A multilocus genetic risk score predicts coronary heart disease risk in a Chinese Han population.
Atherosclerosis - 1 Dec 2014
Gui Lixuan, Wu Fangqin, Han Xu, Dai Xiayun, Qiu Gaokun, Li Jun, Wang Jing, Zhang Xiaoming, Wu Tangchun, He Meian
Abstract excerpt
OBJECTIVE: Genome-wide association studies have identified multiple genetic loci associated with coronary heart disease (CHD) risk. However, whether these loci could improve the CHD risk prediction is unclear. METHODS AND RESULTS: The present case-control study (1146 CHD cases and 1146 controls) genotyped 19 recently discovered SNPs that associated with CHD risk. As a result, 10 SNPs were successfully replicated...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
