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Article

Comparison of genetic risk prediction models to improve prediction of coronary heart disease in two large cohorts of the MONICA/KORA study.

Genetic epidemiology - 1 Sept 2021

Bauer Alina, Zierer Astrid, Gieger Christian, Büyüközkan Mustafa, Müller-Nurasyid Martina, Grallert Harald, Meisinger Christa, Strauch Konstantin, Prokisch Holger, Roden Michael, Peters Annette, Krumsiek Jan, Herder Christian, Koenig Wolfgang, Thorand Barbara, Huth Cornelia

Abstract excerpt

It is still unclear how genetic information, provided as single-nucleotide polymorphisms (SNPs), can be most effectively integrated into risk prediction models for coronary heart disease (CHD) to add significant predictive value beyond clinical risk models. For the present study, a population-based case-cohort was used as a trainingset (451 incident cases, 1488 noncases) and an independent cohort as testset (160...

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PMID: 34082474
DOI: 10.1002/gepi.22389

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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