Literature-based genetic risk scores for coronary heart disease: the Cardiovascular Registry Maastricht (CAREMA) prospective cohort study.

doi:10.1161/CIRCGENETICS.111.960708

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Article

Literature-based genetic risk scores for coronary heart disease: the Cardiovascular Registry Maastricht (CAREMA) prospective cohort study.

Circulation. Cardiovascular genetics - 1 Apr 2012

Vaarhorst Anika A M, Lu Yingchang, Heijmans Bastiaan T, Dollé Martijn E T, Böhringer Stefan, Putter Hein, Imholz Sandra, Merry Audrey H H, van Greevenbroek Marleen M, Jukema J Wouter, Gorgels Anton P M, van den Brandt Piet A, Müller Michael, Schouten Leo J, Feskens Edith J M, Boer Jolanda M A, Slagboom P Eline

Abstract excerpt

BACKGROUND: Genome-wide association studies (GWAS) have identified many single-nucleotide polymorphisms (SNPs) associated with coronary heart disease (CHD) or CHD risk factors (RF). Using a case-cohort study within the prospective Cardiovascular Registry Maastricht (CAREMA) cohort, we tested if genetic risk scores (GRS) based on GWAS-identified SNPs are associated with and predictive for future CHD. METHODS AND...

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PMID: 22373668
DOI: 10.1161/CIRCGENETICS.111.960708

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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