Article
Next-generation sequencing to assess HIV tropism.
Current opinion in HIV and AIDS - 1 Sept 2012
Swenson Luke C, Däumer Martin, Paredes Roger
Abstract excerpt
PURPOSE OF REVIEW: Deep sequencing of the V3 region of the HIV envelope gene can detect minority non-R5 variants in patients with high sensitivity and specificity. As next-generation sequencing approaches have matured, the clinical utility of deep sequencing for HIV tropism has entered the clinic. Accurate and sensitive tropism testing is essential for successful treatment with the CCR5 antagonist class of...
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