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Article

Reliable genotypic tropism tests for the major HIV-1 subtypes.

Scientific reports - 25 Feb 2015

Cashin Kieran, Gray Lachlan R, Harvey Katherine L, Perez-Bercoff Danielle, Lee Guinevere Q, Sterjovski Jasminka, Roche Michael, Demarest James F, Drummond Fraser, Harrigan P Richard, Churchill Melissa J, Gorry Paul R

Abstract excerpt

Over the past decade antiretroviral drugs have dramatically improved the prognosis for HIV-1 infected individuals, yet achieving better access to vulnerable populations remains a challenge. The principal obstacle to the CCR5-antagonist, maraviroc, from being more widely used in anti-HIV-1 therapy regimens is that the pre-treatment genotypic "tropism tests" to determine virus susceptibility to maraviroc have been...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25712827
DOI: 10.1038/srep08543
PMCID: PMC4894445

Genes

CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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