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Article

Genotypic inference of HIV-1 tropism using population-based sequencing of V3.

Journal of visualized experiments : JoVE - 27 Dec 2010

McGovern Rachel A, Harrigan P Richard, Swenson Luke C

Abstract excerpt

BACKGROUND: Prior to receiving a drug from CCR5-antagonist class in HIV therapy, a patient must undergo an HIV tropism test to confirm that his or her viral population uses the CCR5 coreceptor for cellular entry, and not an alternative coreceptor. One approach to tropism testing is to examine the sequence of the V3 region of the HIV envelope, which interacts with the coreceptor. METHODS: Viral RNA is extracted...

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Share to CCR5 Receptor Antagonists
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, CCR5

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Source

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Identifiers

PMID: 21248683
DOI: 10.3791/2531
PMCID: PMC3159650

Genes

CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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