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Article

A transposon-based analysis of gene mutations related to skin cancer development.

The Journal of investigative dermatology - 1 Jan 2013

Quintana Rita M, Dupuy Adam J, Bravo Ana, Casanova M Llanos, Alameda Josefa P, Page Angustias, Sánchez-Viera Miguel, Ramírez Angel, Navarro Manuel

Abstract excerpt

Nonmelanoma skin cancer (NMSC) is by far the most frequent type of cancer in humans. NMSC includes several types of malignancies with different clinical outcomes, the most frequent being basal and squamous cell carcinomas. We have used the Sleeping Beauty transposon/transposase system to identify somatic mutations associated with NMSC. Transgenic mice bearing multiple copies of a mutagenic Sleeping Beauty...

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Identifiers

PMID: 22832494
DOI: 10.1038/jid.2012.245

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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