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Identification of cancer driver genes using Sleeping Beauty transposon mutagenesis.

Cancer science - 1 Jun 2021

Takeda Haruna, Jenkins Nancy A, Copeland Neal G

Abstract excerpt

Cancer genome sequencing studies have identified driver genes for a variety of different cancers and helped to understand the genetic landscape of human cancer. It is still challenging, however, to identify cancer driver genes with confidence simply from genetic data alone. In vivo forward genetic screens using Sleeping Beauty (SB) transposon mutagenesis provides another powerful genetic tool for identifying...

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Share to Disease Progression
Share to DNA Transposable Elements
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33783919
DOI: 10.1111/cas.14901
PMCID: PMC8177796

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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