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Article

Transposon mutagenesis disentangles osteosarcoma genetic drivers.

Nature genetics - 1 Jun 2015

Jones Kevin B

Abstract excerpt

The genetic drivers of osteosarcoma have been difficult to identify because of the genomic complexity consistently encountered in cancer cells at diagnosis. A new study uses Sleeping Beauty transposon mutagenesis to drive osteosarcomagenesis in the mouse and identify likely drivers of the disease in humans.

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Identifiers

PMID: 26018893
DOI: 10.1038/ng.3317

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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