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Article

Systematic analysis of FKBP inducible degradation domain tagging strategies for the human malaria parasite Plasmodium falciparum.

PloS one - 1 Jan 2012

de Azevedo Mauro Ferreira, Gilson Paul R, Gabriel Heloisa B, Simões Roseli F, Angrisano Fiona, Baum Jacob, Crabb Brendan S, Wunderlich Gerhard

Abstract excerpt

Targeted regulation of protein levels is an important tool to gain insights into the role of proteins essential to cell function and development. In recent years, a method based on mutated forms of the human FKBP12 has been established and used to great effect in various cell types to explore protein function. The mutated FKBP protein, referred to as destabilization domain (DD) tag when fused with a native...

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Identifiers

PMID: 22815885
DOI: 10.1371/journal.pone.0040981
PMCID: PMC3397994

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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