Article

Evidence that disruption of apicoplast protein import in malaria parasites evades delayed-death growth inhibition

2018-09-21

Abstract excerpt

Malaria parasites ( Plasmodium spp.) contain a nonphotosynthetic plastid organelle called the apicoplast, which houses essential metabolic pathways and is required throughout the parasite life cycle. Hundreds of proteins are imported across 4 membranes into the apicoplast to support its function and biogenesis. The machinery that mediates this import process is distinct from proteins in the human host and may ser...

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Literature Corpus work: 68c7d111-53c6-58a7-9c3b-6faf962ef301
DOI: 10.1101/422618

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