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Some conditions apply: Systems for studying Plasmodium falciparum protein function

22 Apr 2021

Abstract excerpt

Malaria, caused by infection with Plasmodium parasites, remains a significant global health concern. For decades, genetic intractability and limited tools hindered our ability to study essential proteins and pathways in Plasmodium falciparum, the parasite associated with the most severe malaria cases. However, recent years have seen major leaps forward in the ability to genetically manipulate P. falciparum...

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PMID: 33886685
DOI: 10.1371/journal.ppat.1009442

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