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Article

Identification and Characterization of a Liver Stage-Specific Promoter Region of the Malaria Parasite Plasmodium

27 Oct 2010

Abstract excerpt

During the blood meal of a Plasmodium-infected mosquito, 10 to 100 parasites are inoculated into the skin and a proportion of these migrate via the bloodstream to the liver where they infect hepatocytes. The Plasmodium liver stage, despite its clinical silence, represents a highly promising target for antimalarial drug and vaccine approaches. Successfully invaded parasites undergo a massive proliferation in...

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PMID: 21048918
DOI: 10.1371/journal.pone.0013653

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