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Article

Impaired neurovascular coupling in the APPxPS1 mouse model of Alzheimer's disease.

Current Alzheimer research - 1 Dec 2012

Rancillac Armelle, Geoffroy Helene, Rossier Jean

Abstract excerpt

The tight coupling between neuronal activity and the local increase of blood flow termed neurovascular coupling is essential for normal brain function. This mechanism of regulation is compromised in Alzheimer's Disease (AD). In order to determine whether a purely vascular dysfunction or a neuronal alteration of blood vessels diameter control could be responsible for the impaired neurovascular coupling observed in...

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PMID: 22799606
DOI: 10.2174/156720512804142859

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NPY

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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