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Article

Alterations in vascular reactivity in single- and double-transgenic mice coexpressing human APP-C100 and mutant SOD(1) genes.

Chinese medical journal - 1 May 2002

Xue Shouru, Li Qiaoxin, Khalil Zeinab

Abstract excerpt

OBJECTIVE: To explore the mechanism underlying changes in microvascular reactivity in single- and double-transgenic mice. METHODS: Peripheral vascular reactivity to the vasodilators, acetylcholine and sodium nitroprusside, on perfused microvasculature of the hind footpad was investigated using nontransgenic mice, single-transgenic mice expressing the human APP-C100 (TgC100. WT or TgC100. V717F) and...

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Source

Identifiers

PMID: 12133537

Genes

APP

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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