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Article

Electroacupuncture Prevents Against AD-Like Phenotypes in APP/PS1 Mice: Investigation of the Mechanisms From Cerebral Microangiopathy.

CNS neuroscience & therapeutics - 1 Dec 2025

Yang Chen, Li Baobao, Yang Shaojie, Wang Xuncui, Zhu Guoqi, Wang Jingji

Abstract excerpt

BACKGROUND: Electroacupuncture (EA) has been widely used in Alzheimer's disease (AD) treatment. However, its underlying mechanisms remain poorly elucidated. PURPOSE: This study aimed to investigate the effects of EA on AD-like phenotypes and explore the mechanisms. METHODS: We first evaluated AD-like behaviors and cerebral blood flow (CBF) changes in APPswe/PS1dE9 (APP/PS1) mice at different ages. Subsequently,...

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Identifiers

PMID: 41367129
DOI: 10.1002/cns.70696
PMCID: PMC12689941

Genes

APP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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