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Article

Subcellular localization of yeast CDC46 varies with the cell cycle.

Genes & development - 1 Dec 1990

Hennessy K M, Clark C D, Botstein D

Abstract excerpt

The Saccharomyces cerevisiae CDC46 protein accumulates in the nucleus of nondividing interphase cells. Soon after the cell has become committed to division, there is a rapid disappearance of CDC46 protein from the nucleus. This shift is not a consequence of variation in total CDC46 protein levels and is associated with DNA replication at the G1-S boundary. We propose that the CDC46 protein, which is required for...

Topics

Cell Cycle
Cell Nucleus
DNA Replication
DNA, Fungal
Fungal Proteins
Gene Expression Regulation, Fungal
Genotype
Models, Biological
RNA, Fungal
Restriction Mapping
Saccharomyces cerevisiae

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 2279699
DOI: 10.1101/gad.4.12b.2252

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2279699-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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