Article
Subcellular localization of yeast CDC46 varies with the cell cycle.
Genes & development - 1 Dec 1990
Hennessy K M, Clark C D, Botstein D
Abstract excerpt
The Saccharomyces cerevisiae CDC46 protein accumulates in the nucleus of nondividing interphase cells. Soon after the cell has become committed to division, there is a rapid disappearance of CDC46 protein from the nucleus. This shift is not a consequence of variation in total CDC46 protein levels and is associated with DNA replication at the G1-S boundary. We propose that the CDC46 protein, which is required for...
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