A group of interacting yeast DNA replication genes.

doi:10.1101/gad.5.6.958

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Article

A group of interacting yeast DNA replication genes.

Genes & development - 1 Jun 1991

Hennessy K M, Lee A, Chen E, Botstein D

Abstract excerpt

Mutations in the cell-division-cycle genes CDC46 and CDC47 were originally isolated as suppressors of mutations in two other cell-division-cycle genes (CDC45 and CDC54). We found several combinations of mutations in these genes that result in allele-specific suppression and synthetic lethality, confirming that this set of genes forms a group of genetically interacting components. Here, we show that the other...

Topics

Alleles
Amino Acid Sequence
Animals
Base Sequence
Cell Cycle
Cell Cycle Proteins
Chromosome Mapping
DNA Replication
DNA, Fungal
Fungal Proteins
Genes, Fungal
Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Mutation

Phenotype

Rabbits

Restriction Mapping

Saccharomyces cerevisiae

Source

Open in PubMed

Identifiers

PMID: 2044962
DOI: 10.1101/gad.5.6.958

Genes

CDC45

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2044962-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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