Cell cycle regulation of the yeast Cdc7 protein kinase by association with the Dbf4 protein.

doi:10.1128/mcb.13.5.2899-2908.1993

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Article

Cell cycle regulation of the yeast Cdc7 protein kinase by association with the Dbf4 protein.

Molecular and cellular biology - 1 May 1993

Jackson A L, Pahl P M, Harrison K, Rosamond J, Sclafani R A

Abstract excerpt

Yeast Cdc7 protein kinase and Dbf4 protein are both required for the initiation of DNA replication at the G1/S phase boundary of the mitotic cell cycle. Cdc7 kinase function is stage-specific in the cell cycle, but total Cdc7 protein levels remained unchanged. Therefore, regulation of Cdc7 function appears to be the result of posttranslational modification. In this study, we have attempted to elucidate the...

Topics

Cell Cycle
Cell Cycle Proteins
Crosses, Genetic
DNA Replication
DNA-Binding Proteins
Ethyl Methanesulfonate
Fungal Proteins
G1 Phase
Genes, Fungal
Genotype
Kinetics
Mating Factor
Mutagenesis
Peptides

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pheromones

Plasmids

Protein Kinases

Protein Serine-Threonine Kinases

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Identifiers

PMID: 8474449
DOI: 10.1128/mcb.13.5.2899-2908.1993
PMCID: PMC359683

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