Article
The Cdc6 protein is ubiquitinated in vivo for proteolysis in Saccharomyces cerevisiae.
The Journal of biological chemistry - 26 Mar 1999
Sánchez M, Calzada A, Bueno A
Abstract excerpt
The Saccharomyces cerevisiae Cdc6 protein is necessary for the formation of pre-replicative complexes that are required for firing DNA replication at origins at the beginning of S phase. Cdc6p protein levels oscillate during the cell cycle. In a normal cell cycle the presence of this protein is restricted to G1, partly because the CDC6 gene is transcribed only during G1 and partly because the Cdc6p protein is...
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