The Cdc6 protein is ubiquitinated in vivo for proteolysis in Saccharomyces cerevisiae.

doi:10.1074/jbc.274.13.9092

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Article

The Cdc6 protein is ubiquitinated in vivo for proteolysis in Saccharomyces cerevisiae.

The Journal of biological chemistry - 26 Mar 1999

Sánchez M, Calzada A, Bueno A

Abstract excerpt

The Saccharomyces cerevisiae Cdc6 protein is necessary for the formation of pre-replicative complexes that are required for firing DNA replication at origins at the beginning of S phase. Cdc6p protein levels oscillate during the cell cycle. In a normal cell cycle the presence of this protein is restricted to G1, partly because the CDC6 gene is transcribed only during G1 and partly because the Cdc6p protein is...

Topics

Cell Cycle Proteins
DNA Replication
F-Box Proteins
Flow Cytometry
Fungal Proteins
Immunoblotting
Interphase
Mutation
S Phase
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins
Ubiquitin-Protein Ligases
Ubiquitins

Source

Open in PubMed

Identifiers

PMID: 10085159
DOI: 10.1074/jbc.274.13.9092

Genes

CDC6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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