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Article

Heparin-induced thrombocytopenia: the role of platelets genetic polymorphisms.

Platelets - 1 Jan 2013

Pamela Scarparo, Anna Maria Lombardi, Elena Duner, Giovanni Malerba, Emanuele Allemand, Silvia Vettore, Carmen Blumentritt, Andreas Greinacher, Fabrizio Fabris

Abstract excerpt

Heparin-induced thrombocytopenia (HIT) is a severe complication of heparin therapy, characterized by thrombocytopenia and an increased risk for thrombotic complications secondary to the formation of IgG antibodies (Ab), recognizing a complex of heparin (H) and PF4. Using the 4T clinical score for HIT and the presence of heparin-associated Ab assayed by enzyme-linked immunosorbent assay and heparin-induced...

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Source

Identifiers

PMID: 22793995
DOI: 10.3109/09537104.2012.701026

Genes

PECAM1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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