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Article

On the role of platelet Fc gamma RIIa phenotype in heparin-induced thrombocytopenia.

Thrombosis and haemostasis - 1 Dec 1995

Brandt J T, Isenhart C E, Osborne J M, Ahmed A, Anderson C L

Abstract excerpt

Heparin induced thrombocytopenia (HIT) is characterized by the formation of antibodies that activate normal donor platelets in vitro in the presence of heparin. We asked whether the commonly observed donor-specific variation in the platelet aggregation response to HIT antibodies is influenced by...

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PMID: 8772238

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-8772238-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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On the role of platelet Fc gamma RIIa phenotype in heparin-induced thrombocytopenia.PMID 8772238Read ↗

Importance of the FcgammaRIIa-Arg/His-131 polymorphism in heparin-induced thrombocytopenia diagnosis.Semantic proximity Read ↗

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Single amino acid mutation of Fc gamma receptor is associated with the development of heparin-induced thrombocytopenia.Semantic proximity Read ↗

Platelet FcgammaRIIA His131Arg polymorphism and platelet function: antibodies to platelet-bound fibrinogen induce platelet activation.Semantic proximity Read ↗

Heparin-induced thrombocytopenia: the role of platelets genetic polymorphisms.Semantic proximity Read ↗

Polymorphism of the Fcγ Receptor II as a Possible Predisposing Factor for Heparin-Induced Thrombocytopenia.Semantic proximity Read ↗

The platelet Fc receptor, FcγRIIa.Semantic proximity Read ↗

A naturally occurring mutation in Fc gamma RIIA: a Q to K127 change confers unique IgG binding properties to the R131 allelic form of the receptor.Semantic proximity Read ↗

Polymorphisms of protein tyrosine phosphatase CD148 influence FcγRIIA-dependent platelet activation and the risk of heparin-induced thrombocytopenia.Semantic proximity Read ↗

Response of human platelets to activating monoclonal antibodies: importance of Fc gamma RII (CD32) phenotype and level of expression.Semantic proximity Read ↗

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