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Article

Importance of the FcgammaRIIa-Arg/His-131 polymorphism in heparin-induced thrombocytopenia diagnosis.

Thrombosis and haemostasis - 1 Mar 1998

Bachelot-Loza C, Saffroy R, Lasne D, Chatellier G, Aiach M, Rendu F

Abstract excerpt

Heparin-induced thrombocytopenia (HIT) involves heparin-dependent antibodies which induce platelet activation. In the present study, we searched for a relationship between the polymorphism of the Fc receptor (FcgammaRIIa) and the development of HIT. In this purpose, all the donors were genotyped...

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Identifiers

PMID: 9531034

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-9531034-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Importance of the FcgammaRIIa-Arg/His-131 polymorphism in heparin-induced thrombocytopenia diagnosis.PMID 9531034Read ↗

Heparin-induced thrombocytopenia: new insights into the impact of the FcgammaRIIa-R-H131 polymorphism.Semantic proximity Read ↗

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Increased risk of thrombosis in FcγRIIA 131RR patients with HIT due to defective control of platelet activation by plasma IgG2.Semantic proximity Read ↗

Polymorphism of the Fcγ Receptor II as a Possible Predisposing Factor for Heparin-Induced Thrombocytopenia.Semantic proximity Read ↗

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Heparin-induced thrombocytopenia: the role of platelets genetic polymorphisms.Semantic proximity Read ↗

The platelet Fc receptor, FcγRIIa.Semantic proximity Read ↗

Single amino acid mutation of Fc gamma receptor is associated with the development of heparin-induced thrombocytopenia.Semantic proximity Read ↗

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Development of a real-time PCR detection method for a FCGR2A polymorphism in the LightCycler and application in the heparin-induced thrombocytopenia syndrome.Semantic proximity Read ↗

Platelet FcgammaRIIA His131Arg polymorphism and platelet function: antibodies to platelet-bound fibrinogen induce platelet activation.Semantic proximity Read ↗

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