Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Altered acquisition and extinction of amphetamine-paired context conditioning in genetic mouse models of altered NMDA receptor function.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Oct 2012

Benneyworth Michael A, Coyle Joseph T

Abstract excerpt

Repeated intermittent exposure to amphetamine (AMPH) results in the development of persistent behavioral and neurological changes. When drug exposure is paired with a specific environment, contextual cues can control conditioned responses, context-specific sensitization, and alterations in dendritic morphology in the nucleus accumbens (NAc). Intact N-methyl-D-aspartate (NMDA) glutamate receptor signaling is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amphetamine
Share to Behavioral Symptoms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Conditioning, Psychological

Share to Dendritic Spines

Share to Extinction, Psychological

Share to Hyperkinesis

Share to Nucleus Accumbens

Share to Silver Staining

Source

Open in PubMed Open full text

Identifiers

PMID: 22763616
DOI: 10.1038/npp.2012.108
PMCID: PMC3442344

Genes

AMPH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Altered acquisition and extinction of amphetamine-paired context conditioning in genetic mouse models of altered NMDA receptor function.PMID 22763616Read ↗

A crucial role for forebrain adenosine A(2A) receptors in amphetamine sensitization.Semantic proximity Read ↗

Behavioral phenotyping and dopamine dynamics in mice with conditional deletion of the glutamate transporter GLT-1 in neurons: resistance to the acute locomotor effects of amphetamine.Semantic proximity Read ↗

Locomotor conditioning by amphetamine requires cyclin-dependent kinase 5 signaling in the nucleus accumbens.Semantic proximity Read ↗

alpha(2A)-Adrenoceptors regulate d-amphetamine-induced hyperactivity and behavioural sensitization in mice.Semantic proximity Read ↗

Conditioned place preference and locomotor activity in response to methylphenidate, amphetamine and cocaine in mice lacking dopamine D4 receptors.Semantic proximity Read ↗

Amphetamine-evoked c-fos mRNA expression in the caudate-putamen: the effects of DA and NMDA receptor antagonists vary as a function of neuronal phenotype and environmental context.Semantic proximity Read ↗

Adolescence: a time of transition for the phenotype of dcc heterozygous mice.Semantic proximity Read ↗

Amphetamine modulation of long-term potentiation in the prefrontal cortex: dose dependency, monoaminergic contributions, and paradoxical rescue in hyperdopaminergic mutant.Semantic proximity Read ↗

Prefrontal glutamate correlates of methamphetamine sensitization and preference.Semantic proximity Read ↗

Subchronic amphetamine decreases hyperactivity, anti-social behaviour and anhedonia in dopamine transporter knockout rats: role of prefrontal glutamateSemantic proximity Read ↗

Brain-specific overexpression of trace amine-associated receptor 1 alters monoaminergic neurotransmission and decreases sensitivity to amphetamine.Semantic proximity Read ↗

Reversal of morphine-induced cell-type-specific synaptic plasticity in the nucleus accumbens shell blocks reinstatement.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.