Article
Conditioned place preference and locomotor activity in response to methylphenidate, amphetamine and cocaine in mice lacking dopamine D4 receptors.
Journal of psychopharmacology (Oxford, England) - 1 Jun 2010
Thanos P K, Bermeo C, Rubinstein M, Suchland K L, Wang G J, Grandy D K, Volkow N D
Abstract excerpt
Methylphenidate (MP) and amphetamine (AMPH) are the most frequently prescribed medications for the treatment of attention-deficit/hyperactivity disorder (ADHD). Both drugs are believed to derive their therapeutic benefit by virtue of their dopamine (DA)-enhancing effects, yet an explanation for the observation that some patients with ADHD respond well to one medication but not to the other remains elusive. The...
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