Article
The association of CYP2D6 genotype and postoperative nausea and vomiting in orthopedic trauma patients.
Biological research for nursing - 1 Oct 2013
Wesmiller Susan W, Henker Richard A, Sereika Susan M, Donovan Heidi S, Meng Li, Gruen Gary S, Tarkin Ivan S, Conley Yvette P
Abstract excerpt
The CYP2D6 gene encodes for an enzyme that is involved in the metabolism of more than 25% of all medications, including many opioids and antiemetics. It may contribute to the risk of postoperative nausea and vomiting (PONV), a common surgical complication. However, little research has been conducted in this area. The purpose of this study was to explore the association of CYP2D6 genotypes with PONV in adult...
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