Article
CYP2D6 poor metabolizer genotype and smoking predict severe postoperative pain in female patients on arrival to the recovery room.
Pain medicine (Malden, Mass.) - 1 Apr 2012
Yang Zongqi, Yang Zhe, Arheart Kristopher L, Morris Richard, Zhang Yanping, Rodriguez Yiliam, Song Chunyu, Gitlin Melvin C, Candiotti Keith A
Abstract excerpt
UNLABELLED: Recent studies have shown that CYP2D6 acts at critical steps for endogenous morphine biosynthesis. The present study assessed the contribution of CYP2D6 genetic polymorphisms, smoking, and other factors on acute severe postoperative pain (linear analog pain scores ≥8). METHODS: Two hu...
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