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Article

Impact of CYP2D6 genotype on postoperative tramadol analgesia.

Pain - 1 Sept 2003

Stamer Ulrike M, Lehnen Katja, Höthker Fabienne, Bayerer Bettina, Wolf Stephanie, Hoeft Andreas, Stuber Frank

Abstract excerpt

Genetic polymorphisms result in absent enzyme activity of CYP2D6 (poor metabolizers, PM) in about 10% of the Caucasian population. This study investigates whether the PM genotype has an impact on the response to tramadol analgesia in postoperative patients. A prospective study design was used and...

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Source

Identifiers

PMID: 14499440
DOI: 10.1016/s0304-3959(03)00212-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-14499440-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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