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Article

CYP2D6 isoenzyme and ABCB1 gene polymorphisms associated with postoperative nausea and vomiting in women undergoing laparoscopic cholecystectomy: a randomized trial.

Brazilian journal of anesthesiology (Elsevier) - 1 Jan 2000

Ribeiro Angela Henrique Silva, Braga Estêvão Luiz Carvalho, Ferreira Nathalia de Araújo Gouveia, Olej Beni, Verçosa Nubia, Antunes Leonardo Dos Santos, Cavalcanti Ismar Lima

Abstract excerpt

INTRODUCTION: Postoperative nausea and vomiting is still a common complication. Serotonin receptor antagonists are commonly used in clinical practice for antiemetic prophylaxis. Interindividual variations in drug response, including single nucleotide polymorphisms, are related to pharmacokinetic and pharmacodynamic changes in these drugs and may lead to a poor therapeutic response. This study aimed to evaluate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 36841429
DOI: 10.1016/j.bjane.2023.02.002
PMCID: PMC11148501

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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