Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Impact of pharmacogenomic profiles on post-surgical pain following laparotomy for gynecologic pathology.

Gynecologic oncology - 1 Apr 2024

Glaser Gretchen E, Maddy Brandon, Kumar Amanika, Ishitani Karen, Lemens Maureen A, Hanson Kristine, Moyer Ann M, Habermann Elizabeth, Dowdy Sean C

Abstract excerpt

OBJECTIVES: The aim of this prospective study was to compare perioperative opioid use in women by status of CYP2D6, a highly polymorphic pharmacogene relevant to opioid metabolism. METHODS: Patients undergoing laparotomy were prospectively recruited and provided a preoperative saliva swab for a pharmacogenomic (PGx) gene panel. Postoperative opioid usage and pain scores were evaluated via chart review and a phone...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Analgesics, Opioid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP2D6

Share to Genital Neoplasms, Female

Share to Genotype

Share to Pain, Postoperative

Share to Pharmacogenetics

Source

Identifiers

PMID: 38479169
DOI: 10.1016/j.ygyno.2024.03.001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Impact of pharmacogenomic profiles on post-surgical pain following laparotomy for gynecologic pathology.PMID 38479169Read ↗

CYP2D6 poor metabolizer genotype and smoking predict severe postoperative pain in female patients on arrival to the recovery room.Semantic proximity Read ↗

The impact of CYP2D6 genetic polymorphisms on postoperative morphine consumption.Semantic proximity Read ↗

Pharmacogenetics-guided analgesics in major abdominal surgery: Further benefits within an enhanced recovery protocol.Semantic proximity Read ↗

Impact of CYP2D6 and CYP2B6 phenotypes on the response to tramadol in patients with acute post-surgical pain.Semantic proximity Read ↗

Cytochrome P450 2D6 Genotyping for Post-Operative Opioids.Semantic proximity Read ↗

Influence of CYP2D6 phenotype on the pharmacokinetics and pharmacodynamics of tramadol in patients treated for post-operative pain management.Semantic proximity Read ↗

CYP2D6 genotype dependent oxycodone metabolism in postoperative patients.Semantic proximity Read ↗

Reviewing pharmacogenetics to advance precision medicine for opioidsSemantic proximity Read ↗

Sex Differences in Associations Between CYP2D6 Phenotypes and Response to Opioid AnalgesicsSemantic proximity Read ↗

Utilization of pharmacogenomics and therapeutic drug monitoring for opioid pain management.Semantic proximity Read ↗

Impact of the CYP2D6 genotype on post-operative intravenous oxycodone analgesia.Semantic proximity Read ↗

A hybrid implementation-effectiveness randomized trial of CYP2D6-guided postoperative pain management.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.