Article

Distribution of CYP2D6 multiplication, CYP2D6*5, and clinical implications in postoperative patients receiving tramadol analgesia in the Minangkabau ethnic group, Indonesia

2024-12-17

Abstract excerpt

<h4>Background: </h4> Cytochrome P450 2D6 (CYP2D6) is an important enzyme that metabolizes commonly used drugs, such as tramadol hydrochloride (a widely used opioid analgesic). Genetic polymorphisms of CYP2D6 have been shown to influence the pharmacodynamic properties of administered drugs. This study aimed to screen 63 postoperative patients (wild-type, CYP2D6*5, and CYP2D6 multiplication) of Minangkabau ethnicit...

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Literature Corpus work: 6d459ba7-56ee-5f79-b538-add131a60735
DOI: 10.12688/f1000research.155988.1

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Distribution of CYP2D6 multiplication, CYP2D6*5, and clinical implications in postoperative patients receiving tramadol analgesia in the Minangkabau ethnic group, IndonesiaDOI 10.12688/f1000research.155988.1Read

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