Article
Positive roles for negative regulators in the mating response of yeast.
Molecular systems biology - 5 Jun 2012
Houser John R, Ford Eintou, Nagiec Michal J, Errede Beverly, Elston Timothy C
Abstract excerpt
All cells must detect and respond to changes in their environment, often through changes in gene expression. The yeast pheromone pathway has been extensively characterized, and is an ideal system for studying transcriptional regulation. Here we combine computational and experimental approaches to study transcriptional regulation mediated by Ste12, the key transcription factor in the pheromone response. Our...
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