Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The scaffold protein Ste5 directly controls a switch-like mating decision in yeast.

Nature - 6 May 2010

Malleshaiah Mohan K, Shahrezaei Vahid, Swain Peter S, Michnick Stephen W

Abstract excerpt

Evolution has resulted in numerous innovations that allow organisms to increase their fitness by choosing particular mating partners, including secondary sexual characteristics, behavioural patterns, chemical attractants and corresponding sensory mechanisms. The haploid yeast Saccharomyces cerevisiae selects mating partners by interpreting the concentration gradient of pheromone secreted by potential mates...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Models, Biological
Share to Phosphorylation
Share to Mitogen-Activated Protein Kinases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Adaptor Proteins, Signal Transducing

Share to Protein Phosphatase 2

Share to Reproduction

Share to Saccharomyces cerevisiae

Share to Saccharomyces cerevisiae Proteins

Source

Identifiers

PMID: 20400943
DOI: 10.1038/nature08946

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The scaffold protein Ste5 directly controls a switch-like mating decision in yeast.PMID 20400943Read ↗

The Ste5 scaffold allosterically modulates signaling output of the yeast mating pathway.Semantic proximity Read ↗

Control of MAPK signaling specificity by a conserved residue in the MEK-binding domain of the yeast scaffold protein Ste5.Semantic proximity Read ↗

Fus3-triggered Tec1 degradation modulates mating transcriptional output during the pheromone response.Semantic proximity Read ↗

Fus3-regulated Tec1 degradation through SCFCdc4 determines MAPK signaling specificity during mating in yeast.Semantic proximity Read ↗

Membrane localization of scaffold proteins promotes graded signaling in the yeast MAP kinase cascade.Semantic proximity Read ↗

Mitogen-activated protein kinase (MAPK) dynamics determine cell fate in the yeast mating response.Semantic proximity Read ↗

Dynamics and organization of MAP kinase signal pathways.Semantic proximity Read ↗

Pheromone-dependent destruction of the Tec1 transcription factor is required for MAP kinase signaling specificity in yeast.Semantic proximity Read ↗

Phenotypic and transcriptional plasticity directed by a yeast mitogen-activated protein kinase network.Semantic proximity Read ↗

MAPK-mediated bimodal gene expression and adaptive gradient sensing in yeast.Semantic proximity Read ↗

Pheromone signaling mechanisms in yeast: a prototypical sex machine.Semantic proximity Read ↗

Dual role for membrane localization in yeast MAP kinase cascade activation and its contribution to signaling fidelity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.